Human Population Genetic Structure and Inference of Group Membership

Human population genetic structure and inference of group membership.

A major goal of biomedical research is to develop the capability to provide highly personalized health care. To do so, it is necessary to understand the distribution of interindividual genetic variation at loci underlying physical characteristics, disease susceptibility, and response to treatment. Variation at these loci commonly exhibits geographic structuring and may contribute to phenotypic ...

Bayesian approach to inference of population structure

Methods of inferring the population structure‎, ‎its applications in identifying disease models as well as foresighting the physical and mental situation of human beings have been finding ever-increasing importance‎. ‎In this article‎, ‎first‎, ‎motivation and significance of studying the problem of population structure is explained‎. ‎In the next section‎, ‎the applications of inference of p...

Population Genetic Inference

Members of the Department of Statistics will be teaching a graduate-level course of eight lectures introducing the theory and techniques of population genetic inference with particular emphasis on modern developments in the field of human genetics. Lectures of 90 minutes will be held at 2pm on Tuesdays in Lecture Theatre C in the Department of Zoology on South Parks Road. No registration is req...

Principles of population genetic inference

Genetic Diversity and Population Structure of Iranian tulips revealed by EST-SSR and NBS-LRR Markers

The genus Tulipa L. (Liliaceae) comprises about 100 species and Iran is considered as one of the main origins of tulips. In this research, genetic diversity and population structure of 27 wild populations of tulips collected from Iran were studied by 15 highly polymorphic and reproducible expressed sequenced tag-simple sequence repeat (EST-SSR) markers and 8 nucleotide binding site (NBS)-enzyme...